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Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians

Of the 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5–15% will develop active tuberculosis (TB). Approximately half will progress to active TB within the first 18 months after infection, presumably because they fail to mount an effective initial immune response. Here, in a...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Luo, Yang, Suliman, Sara, Asgari, Samira, Amariuta, Tiffany, Baglaenko, Yuriy, Martínez-Bonet, Marta, Ishigaki, Kazuyoshi, Gutierrez-Arcelus, Maria, Calderon, Roger, Lecca, Leonid, León, Segundo R., Jimenez, Judith, Yataco, Rosa, Contreras, Carmen, Galea, Jerome T., Becerra, Mercedes, Nejentsev, Sergey, Nigrovic, Peter A., Moody, D. Branch, Murray, Megan B., Raychaudhuri, Soumya
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704092/
https://ncbi.nlm.nih.gov/pubmed/31434886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11664-1
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