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Zero-inflated generalized Dirichlet multinomial regression model for microbiome compositional data analysis

There is heightened interest in using high-throughput sequencing technologies to quantify abundances of microbial taxa and linking the abundance to human diseases and traits. Proper modeling of multivariate taxon counts is essential to the power of detecting this association. Existing models are lim...

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Dettagli Bibliografici
Pubblicato in:Biostatistics
Autori principali: Tang, Zheng-Zheng, Chen, Guanhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410344/
https://ncbi.nlm.nih.gov/pubmed/29939212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxy025
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