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Zero-inflated generalized Dirichlet multinomial regression model for microbiome compositional data analysis

There is heightened interest in using high-throughput sequencing technologies to quantify abundances of microbial taxa and linking the abundance to human diseases and traits. Proper modeling of multivariate taxon counts is essential to the power of detecting this association. Existing models are lim...

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Detalles Bibliográficos
Publicado en:Biostatistics
Main Authors: Tang, Zheng-Zheng, Chen, Guanhua
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410344/
https://ncbi.nlm.nih.gov/pubmed/29939212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxy025
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