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Posttranslational modifications define course of prion strain adaptation and disease phenotype
Posttranslational modifications are a common feature of proteins associated with neurodegenerative diseases including prion protein (PrP(C)), tau, and α-synuclein. Alternative self-propagating protein states or strains give rise to different disease phenotypes and display strain-specific subsets of...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7410085/ https://ncbi.nlm.nih.gov/pubmed/32484800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138677 |
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