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Region-Specific Sialylation Pattern of Prion Strains Provides Novel Insight into Prion Neurotropism
Mammalian prions are unconventional infectious agents that invade and replicate in an organism by recruiting a normal form of a prion protein (PrP(C)) and converting it into misfolded, disease-associated state referred to as PrP(Sc). PrP(C) is posttranslationally modified with two N-linked glycans....
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| Published in: | Int J Mol Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7037812/ https://ncbi.nlm.nih.gov/pubmed/32012886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030828 |
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