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Precision metabolome reprogramming for imprecision therapeutics in retinitis pigmentosa

Retinitis pigmentosa (RP), the most common form of rod-cone dystrophy, is caused by greater than 3100 mutations in more than 71 genes, many of which are preferentially expressed in rod photoreceptors. Cone death generally follows rod loss regardless of the underlying pathogenic mutation. Preventing...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Caruso, Salvatore Marco, Ryu, Joseph, Quinn, Peter M.J., Tsang, Stephen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410039/
https://ncbi.nlm.nih.gov/pubmed/32657778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139239
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