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Precision metabolome reprogramming for imprecision therapeutics in retinitis pigmentosa

Retinitis pigmentosa (RP), the most common form of rod-cone dystrophy, is caused by greater than 3100 mutations in more than 71 genes, many of which are preferentially expressed in rod photoreceptors. Cone death generally follows rod loss regardless of the underlying pathogenic mutation. Preventing...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Caruso, Salvatore Marco, Ryu, Joseph, Quinn, Peter M.J., Tsang, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410039/
https://ncbi.nlm.nih.gov/pubmed/32657778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139239
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