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EpCAM-Binding DARPins for Targeted Photodynamic Therapy of Ovarian Cancer

Ovarian cancer is the most lethal gynecological malignancy due to late detection associated with dissemination throughout the abdominal cavity. Targeted photodynamic therapy (tPDT) aimed at epithelial cell adhesion molecule (EpCAM), overexpressed in over 90% of ovarian cancer metastatic lesions, is...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: van den Brand, Dirk, van Lith, Sanne A. M., de Jong, Jelske M., Gorris, Mark A. J., Palacio-Castañeda, Valentina, Couwenbergh, Stijn T., Goldman, Mark R. G., Ebisch, Inge, Massuger, Leon F., Leenders, William P. J., Brock, Roland, Verdurmen, Wouter P. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409335/
https://ncbi.nlm.nih.gov/pubmed/32630661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071762
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