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Equine Alphaherpesviruses Require Activation of the Small GTPases Rac1 and Cdc42 for Intracellular Transport

Viruses utilize host cell signaling to facilitate productive infection. Equine herpesvirus type 1 (EHV-1) has been shown to activate Ca2+ release and phospholipase C upon contact with α4β1 integrins on the cell surface. Signaling molecules, including small GTPases, have been shown to be activated do...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Kolyvushko, Oleksandr, Kelch, Maximilian A., Osterrieder, Nikolaus, Azab, Walid
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409331/
https://ncbi.nlm.nih.gov/pubmed/32645930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8071013
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