KLF4 Coordinates Corneal Epithelial Apical-Basal Polarity and Plane of Cell Division and Is Downregulated in Ocular Surface Squamous Neoplasia

PURPOSE: Previously, we demonstrated that Krüppel-like factor 4 (KLF4) promotes corneal epithelial (CE) homeostasis by suppressing epithelial-mesenchymal transition (EMT) and TGF-β signaling. As TGF-β affects epithelial apicobasal polarity (ABP) and plane of division, we investigated the role of KLF...

Full description

Saved in:
Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Tiwari, Anil, Swamynathan, Sudha, Jhanji, Vishal, Swamynathan, Shivalingappa K.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2020
Subjects:
Cornea
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409308/
https://ncbi.nlm.nih.gov/pubmed/32396634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.5.15
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items