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KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial–Mesenchymal Transition
PURPOSE: The purpose of this study was to test the hypothesis that KLF4 promotes corneal epithelial (CE) cell fate by suppressing the epithelial–mesenchymal transition (EMT), using spatiotemporally regulated CE-specific ablation of Klf4 in Klf4(Δ/ΔCE) (Klf4(LoxP/LoxP)/Krt12(rtTA/rtTA)/Tet-O-Cre) mic...
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| Pubblicato in: | Invest Ophthalmol Vis Sci |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Association for Research in Vision and Ophthalmology
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5455171/ https://ncbi.nlm.nih.gov/pubmed/28549095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-21826 |
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