KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial–Mesenchymal Transition

PURPOSE: The purpose of this study was to test the hypothesis that KLF4 promotes corneal epithelial (CE) cell fate by suppressing the epithelial–mesenchymal transition (EMT), using spatiotemporally regulated CE-specific ablation of Klf4 in Klf4(Δ/ΔCE) (Klf4(LoxP/LoxP)/Krt12(rtTA/rtTA)/Tet-O-Cre) mic...

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Dades bibliogràfiques
Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Tiwari, Anil, Loughner, Chelsea L., Swamynathan, Sudha, Swamynathan, Shivalingappa K.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2017
Matèries:
Cornea
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455171/
https://ncbi.nlm.nih.gov/pubmed/28549095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-21826
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