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Identification of a Clinical Cutoff Value for Multiplex KRAS(G12/G13) Mutation Detection in Colorectal Adenocarcinoma Patients Using Digital Droplet PCR, and Comparison with Sanger Sequencing and PNA Clamping Assay

KRAS (Kirsten rat sarcoma 2 viral oncogene homolog) is a major predictive marker for anti-epidermal growth factor receptor treatment, and determination of KRAS mutational status is crucial for successful management of colorectal adenocarcinoma. More standardized and accurate methods for testing KRAS...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Med
Prif Awduron: Lee, Kyung Ha, Lee, Tae Hee, Choi, Min Kyung, Kwon, In Sun, Bae, Go Eun, Yeo, Min-Kyung
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409004/
https://ncbi.nlm.nih.gov/pubmed/32708359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9072283
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