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Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes
The MC1R/cAMP/MITF pathway is a key determinant for growth, differentiation, and survival of melanocytes and melanoma. MITF-M is the melanocyte-specific isoform of Microphthalmia-associated Transcription Factor (MITF) in human melanoma. Here we use two melanocyte cell lines to show that forced expre...
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| Vydáno v: | Cancers (Basel) |
|---|---|
| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7408466/ https://ncbi.nlm.nih.gov/pubmed/32605315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071719 |
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