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MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma
The phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) pathway is frequently hyper-activated upon vemurafenib treatment of melanoma. We have here investigated the relationship between SRY-box 10 (SOX10), forkhead box 3 (FOXD3) and microphthalmia-associated transcription factor (MITF) in the regul...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342406/ https://ncbi.nlm.nih.gov/pubmed/27391157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10422 |
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