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Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities

Colorectal cancer (CRC) is among the most frequent cancer entities worldwide. Multiple factors are causally associated with CRC development, such as genetic and epigenetic alterations, inflammatory bowel disease, lifestyle and dietary factors. During malignant transformation, the cellular energy met...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Neitzel, Carina, Demuth, Philipp, Wittmann, Simon, Fahrer, Jörg
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408264/
https://ncbi.nlm.nih.gov/pubmed/32610612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071731
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