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Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities

Colorectal cancer (CRC) is among the most frequent cancer entities worldwide. Multiple factors are causally associated with CRC development, such as genetic and epigenetic alterations, inflammatory bowel disease, lifestyle and dietary factors. During malignant transformation, the cellular energy met...

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Publicado en:Cancers (Basel)
Main Authors: Neitzel, Carina, Demuth, Philipp, Wittmann, Simon, Fahrer, Jörg
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408264/
https://ncbi.nlm.nih.gov/pubmed/32610612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071731
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