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Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities

Colorectal cancer (CRC) is among the most frequent cancer entities worldwide. Multiple factors are causally associated with CRC development, such as genetic and epigenetic alterations, inflammatory bowel disease, lifestyle and dietary factors. During malignant transformation, the cellular energy met...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Neitzel, Carina, Demuth, Philipp, Wittmann, Simon, Fahrer, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408264/
https://ncbi.nlm.nih.gov/pubmed/32610612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071731
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