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PLGA Microspheres of hGH of Preserved Native State Prepared Using a Self-Regulated Process

The challenges of formulating recombinant human growth hormone (rhGH) into sustained-release polymeric microspheres include two mutual causal factors, protein denaturing by the formulation process and severe initial burst release related with relative high dose. The stabilizers to protect the protei...

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Библиографические подробности
Опубликовано в: :Pharmaceutics
Главные авторы: Diana, Jebun Nessa, Tao, Ying, Du, Qiran, Wang, Meng, Kumar, Chinta Uday, Wu, Fei, Jin, Tuo
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408169/
https://ncbi.nlm.nih.gov/pubmed/32698347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070683
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