Ipragliflozin-induced improvement of liver steatosis in obese mice may involve sirtuin signaling

BACKGROUND: Sodium glucose cotransporter 2 (SGLT2) inhibitors are newly developed oral antidiabetic drugs. SGLT2 is primarily expressed in the kidneys and reabsorbs approximately 90% of the glucose filtered by the renal glomeruli. SGLT2 inhibitors lower glucose levels independently of insulin action...

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Dades bibliogràfiques
Publicat a:World J Hepatol
Autors principals: Suga, Takayoshi, Sato, Ken, Ohyama, Tatsuya, Matsui, Sho, Kobayashi, Takeshi, Tojima, Hiroki, Horiguchi, Norio, Yamazaki, Yuichi, Kakizaki, Satoru, Nishikido, Ayaka, Okamura, Takashi, Yamada, Masanobu, Kitamura, Tadahiro, Uraoka, Toshio
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2020
Matèries:
Basic Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407917/
https://ncbi.nlm.nih.gov/pubmed/32821334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v12.i7.350
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