MK-0626, a selective DPP-4 inhibitor, attenuates hepatic steatosis in ob/ob mice

AIM: To investigate the mechanism and in vivo effects of MK-0626, a dipeptidyl peptidase-4 inhibitor, on hepatic steatosis using ob/ob mice. METHODS: We analyzed obese (ob/ob) 8-wk-old male mice that had been randomly divided into two groups of ob/ob mice (n = 16 each) and were treated with 1.5 or 3...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Ohyama, Tatsuya, Sato, Ken, Yamazaki, Yuichi, Hashizume, Hiroaki, Horiguchi, Norio, Kakizaki, Satoru, Mori, Masatomo, Kusano, Motoyasu, Yamada, Masanobu
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239511/
https://ncbi.nlm.nih.gov/pubmed/25473177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i43.16227
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