EZH2 in Myeloid Malignancies

Our understanding of the significance of epigenetic dysregulation in the pathogenesis of myeloid malignancies has greatly advanced in the past decade. Enhancer of Zeste Homolog 2 (EZH2) is the catalytic core component of the Polycomb Repressive Complex 2 (PRC2), which is responsible for gene silenci...

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Bibliographic Details
Published in:Cells
Main Authors: Rinke, Jenny, Chase, Andrew, Cross, Nicholas C. P., Hochhaus, Andreas, Ernst, Thomas
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407223/
https://ncbi.nlm.nih.gov/pubmed/32650416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071639
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