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EZH2 in normal hematopoiesis and hematological malignancies
Enhancer of zeste homolog 2 (EZH2), the catalytic subunit of the Polycomb repressive complex 2, inhibits gene expression through methylation on lysine 27 of histone H3. EZH2 regulates normal hematopoietic stem cell self-renewal and differentiation. EZH2 also controls normal B cell differentiation. E...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823035/ https://ncbi.nlm.nih.gov/pubmed/26497210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6198 |
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