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EZH2 in normal hematopoiesis and hematological malignancies
Enhancer of zeste homolog 2 (EZH2), the catalytic subunit of the Polycomb repressive complex 2, inhibits gene expression through methylation on lysine 27 of histone H3. EZH2 regulates normal hematopoietic stem cell self-renewal and differentiation. EZH2 also controls normal B cell differentiation. E...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823035/ https://ncbi.nlm.nih.gov/pubmed/26497210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6198 |
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