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In vivo and in silico characterization of apocynin in reducing organ oxidative stress: A pharmacokinetic and pharmacodynamic study
Apocynin has been widely used in vivo as a Nox2‐contaninig nicotinamide adenine dinucleotide phosphate oxidase inhibitor. However, its time‐dependent tissue distribution and inhibition on organ reactive oxygen species (ROS) production remained unclear. In this study, we examined apocynin pharmacokin...
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| Publicado no: | Pharmacol Res Perspect |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7406636/ https://ncbi.nlm.nih.gov/pubmed/32761799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.635 |
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