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Identification of the In Vivo Pharmacokinetics and Pharmacodynamic Driver of Iclaprim
The neutropenic murine thigh infection model was used to define the pharmacokinetic/pharmacodynamic index linked to efficacy of iclaprim against Staphylococcus aureus ATCC 29213 and Staphylococcus pneumoniae ATCC 10813. The 24-h area under the curve (AUC)/MIC index was most closely linked to efficac...
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發表在: | Antimicrob Agents Chemother |
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Main Authors: | , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
American Society for Microbiology
2018
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5913961/ https://ncbi.nlm.nih.gov/pubmed/29378717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02550-17 |
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