High–molecular weight hyaluronan attenuates tubulointerstitial scarring in kidney injury

Renal fibrosis features exaggerated inflammation, extracellular matrix (ECM) deposition, and peritubular capillary loss. We previously showed that IL-10 stimulates high–molecular weight hyaluronan (HMW-HA) expression by fibroblasts, and we hypothesize that HMW-HA attenuates renal fibrosis by reducin...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Wang, Xinyi, Balaji, Swathi, Steen, Emily H., Blum, Alexander J., Li, Hui, Chan, Christina K., Manson, Scott R., Lu, Thomas C., Rae, Meredith M., Austin, Paul F., Wight, Thomas N., Bollyky, Paul L., Cheng, Jizhong, Keswani, Sundeep G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406305/
https://ncbi.nlm.nih.gov/pubmed/32396531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136345
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