Robust antibody and cellular responses induced by DNA-only vaccination for HIV

BACKGROUND: HVTN 098, a randomized, double-blind, placebo-controlled trial, evaluated the safety, tolerability, and immunogenicity of PENNVAX-GP HIV DNA vaccine, administered with or without plasmid IL-12 (pIL-12), via intradermal (ID) or intramuscular (IM) electroporation (EP) in healthy, HIV-uninf...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: De Rosa, Stephen C., Edupuganti, Srilatha, Huang, Yunda, Han, Xue, Elizaga, Marnie, Swann, Edith, Polakowski, Laura, Kalams, Spyros A., Keefer, Michael C., Maenza, Janine, Lu, Yiwen, Wise, Megan C., Yan, Jian, Morrow, Matthew P., Khan, Amir S., Boyer, Jean D., Humeau, Laurent, White, Scott, Pensiero, Michael, Sardesai, Niranjan Y., Bagarazzi, Mark L., Weiner, David B., Ferrari, Guido, Tomaras, Georgia D., Montefiori, David C., Corey, Lawrence, McElrath, M. Juliana
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Clinical Medicine
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406303/
https://ncbi.nlm.nih.gov/pubmed/32437332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137079
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