Depression and Social Defeat Stress Are Associated with Inhibitory Synaptic Changes in the Nucleus Accumbens

Chronic stress in both humans and rodents induces a robust downregulation of neuroligin-2, a key component of the inhibitory synapse, in the NAc that modifies behavioral coping mechanisms and stress resiliency in mice. Here we extend this observation by examining the role of two other inhibitory syn...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Heshmati, Mitra, Christoffel, Daniel J., LeClair, Katherine, Cathomas, Flurin, Golden, Sam A., Aleyasin, Hossein, Turecki, Gustavo, Friedman, Allyson K., Han, Ming-Hu, Menard, Caroline, Russo, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406280/
https://ncbi.nlm.nih.gov/pubmed/32561672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2568-19.2020
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