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Mefloquine in the nucleus accumbens promotes social avoidance and anxiety-like behavior in mice

Mefloquine continues to be a key drug used for malaria chemoprophylaxis and treatment, despite reports of adverse events like depression and anxiety. It is unknown how mefloquine acts within the central nervous system to cause depression and anxiety or why some individuals are more vulnerable. We sh...

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Publicado en:Neuropharmacology
Autores principales: Heshmati, Mitra, Golden, Sam A., Pfau, Madeline L., Christoffel, Daniel J., Seeley, Elena L., Cahill, Michael E., Khibnik, Lena A., Russo, Scott J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681593/
https://ncbi.nlm.nih.gov/pubmed/26471420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.10.013
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