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Mefloquine in the nucleus accumbens promotes social avoidance and anxiety-like behavior in mice

Mefloquine continues to be a key drug used for malaria chemoprophylaxis and treatment, despite reports of adverse events like depression and anxiety. It is unknown how mefloquine acts within the central nervous system to cause depression and anxiety or why some individuals are more vulnerable. We sh...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Heshmati, Mitra, Golden, Sam A., Pfau, Madeline L., Christoffel, Daniel J., Seeley, Elena L., Cahill, Michael E., Khibnik, Lena A., Russo, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681593/
https://ncbi.nlm.nih.gov/pubmed/26471420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.10.013
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