Depression and Social Defeat Stress Are Associated with Inhibitory Synaptic Changes in the Nucleus Accumbens

Chronic stress in both humans and rodents induces a robust downregulation of neuroligin-2, a key component of the inhibitory synapse, in the NAc that modifies behavioral coping mechanisms and stress resiliency in mice. Here we extend this observation by examining the role of two other inhibitory syn...

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Pubblicato in:J Neurosci
Autori principali: Heshmati, Mitra, Christoffel, Daniel J., LeClair, Katherine, Cathomas, Flurin, Golden, Sam A., Aleyasin, Hossein, Turecki, Gustavo, Friedman, Allyson K., Han, Ming-Hu, Menard, Caroline, Russo, Scott J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406280/
https://ncbi.nlm.nih.gov/pubmed/32561672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2568-19.2020
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