Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis

Rheumatoid arthritis (RA) is characterized by synovial joint inflammation, cartilage damage, and dysregulation of the adaptive immune system. While neutrophil extracellular traps (NETs) have been proposed to play a role in the generation of modified autoantigens and in the activation of synovial fib...

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Publicado en:JCI Insight
Autores principales: Carmona-Rivera, Carmelo, Carlucci, Philip M., Goel, Rishi R., James, Eddie, Brooks, Stephen R., Rims, Cliff, Hoffmann, Victoria, Fox, David A., Buckner, Jane H., Kaplan, Mariana J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406272/
https://ncbi.nlm.nih.gov/pubmed/32484790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139388
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