Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis

Rheumatoid arthritis (RA) is characterized by synovial joint inflammation, cartilage damage, and dysregulation of the adaptive immune system. While neutrophil extracellular traps (NETs) have been proposed to play a role in the generation of modified autoantigens and in the activation of synovial fib...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Carmona-Rivera, Carmelo, Carlucci, Philip M., Goel, Rishi R., James, Eddie, Brooks, Stephen R., Rims, Cliff, Hoffmann, Victoria, Fox, David A., Buckner, Jane H., Kaplan, Mariana J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406272/
https://ncbi.nlm.nih.gov/pubmed/32484790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139388
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