Citrullinated Aggrecan Epitopes as Targets of Auto-reactive CD4+ T cells in Patients with Rheumatoid Arthritis

OBJECTIVE. Recognition of citrullinated antigens such as vimentin, fibrinogen, and alpha-enolase is associated with rheumatoid arthritis (RA). Emerging data suggests that the matrix protein aggrecan is also recognized as a citrullinated antigen. The goal of this study was to directly visualize cit-a...

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Pubblicato in:Arthritis Rheumatol
Autori principali: Rims, Cliff, Uchtenhagen, Hannes, Kaplan, Mariana J., Carmona-Rivera, Carmelo, Carlucci, Philip, Mikecz, Katalin, Markovics, Adrienn, Carlin, Jeffrey, Buckner, Jane H., James, Eddie A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438725/
https://ncbi.nlm.nih.gov/pubmed/30390384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40768
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