Vaccination by Two DerG LEAPS Conjugates Incorporating Distinct Proteoglycan (PG, Aggrecan) Epitopes Provides Therapy by Different Immune Mechanisms in a Mouse Model of Rheumatoid Arthritis

Rheumatoid arthritis (RA) can be initiated and driven by immune responses to multiple antigenic epitopes including those in cartilage proteoglycan (PG, aggrecan) and type II collagen. RA is driven by T helper 1 (Th1) or Th17 pro-inflammatory T cell responses. LEAPS (Ligand Epitope Antigen Presentati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Vaccines (Basel)
Prif Awduron: Zimmerman, Daniel H., Mikecz, Katalin, Markovics, Adrienn, Carambula, Roy E., Ciemielewski, Jason C., Toth, Daniel M., Glant, Tibor T., Rosenthal, Ken S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147650/
https://ncbi.nlm.nih.gov/pubmed/34063326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9050448
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