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Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseases

Neutrophils are the most abundant leukocytes in circulation and represent one of the first lines of defense against invading pathogens. Neutrophils possess a vast arsenal of antimicrobial proteins, which can be released from the cell by a death program termed NETosis. Neutrophil extracellular traps...

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Detalhes bibliográficos
Main Authors: Knight, Jason S., Carmona-Rivera, Carmelo, Kaplan, Mariana J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521997/
https://ncbi.nlm.nih.gov/pubmed/23248629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00380
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