regSNPs-ASB: A Computational Framework for Identifying Allele-Specific Transcription Factor Binding From ATAC-seq Data

Expression quantitative trait loci (eQTL) analysis is useful for identifying genetic variants correlated with gene expression, however, it cannot distinguish between causal and nearby non-functional variants. Because the majority of disease-associated SNPs are located in regulatory regions, they can...

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Bibliografiska uppgifter
I publikationen:Front Bioeng Biotechnol
Huvudupphovsmän: Xu, Siwen, Feng, Weixing, Lu, Zixiao, Yu, Christina Y., Shao, Wei, Nakshatri, Harikrishna, Reiter, Jill L., Gao, Hongyu, Chu, Xiaona, Wang, Yue, Liu, Yunlong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Bioengineering and Biotechnology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405637/
https://ncbi.nlm.nih.gov/pubmed/32850739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00886
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