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Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni

Background. At least 250 million people worldwide suffer from schistosomiasis, caused by Schistosoma worms. Genome sequences for several Schistosoma species are available, including a high-quality annotated reference for Schistosoma mansoni. There is a pressing need to develop a reliable functional...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Sankaranarayanan, Geetha, Coghlan, Avril, Driguez, Patrick, Lotkowska, Magda E., Sanders, Mandy, Holroyd, Nancy, Tracey, Alan, Berriman, Matthew, Rinaldi, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405262/
https://ncbi.nlm.nih.gov/pubmed/32789192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.16031.2
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