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Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni

Background. At least 250 million people worldwide suffer from schistosomiasis, caused by Schistosoma worms. Genome sequences for several Schistosoma species are available, including a high-quality annotated reference for Schistosoma mansoni. There is a pressing need to develop a reliable functional...

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Publicat a:Wellcome Open Res
Autors principals: Sankaranarayanan, Geetha, Coghlan, Avril, Driguez, Patrick, Lotkowska, Magda E., Sanders, Mandy, Holroyd, Nancy, Tracey, Alan, Berriman, Matthew, Rinaldi, Gabriel
Format: Artigo
Idioma:Inglês
Publicat: F1000 Research Limited 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405262/
https://ncbi.nlm.nih.gov/pubmed/32789192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.16031.2
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