Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni

Background. At least 250 million people worldwide suffer from schistosomiasis, caused by Schistosoma worms. Genome sequences for several Schistosoma species are available, including a high-quality annotated reference for Schistosoma mansoni. There is a pressing need to develop a reliable functional...

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Vydáno v:Wellcome Open Res
Hlavní autoři: Sankaranarayanan, Geetha, Coghlan, Avril, Driguez, Patrick, Lotkowska, Magda E., Sanders, Mandy, Holroyd, Nancy, Tracey, Alan, Berriman, Matthew, Rinaldi, Gabriel
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000 Research Limited 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405262/
https://ncbi.nlm.nih.gov/pubmed/32789192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.16031.2
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