Antagonists of the serotonin receptor 5A target human breast tumor initiating cells

BACKGROUND: Breast tumor initiating cells (BTIC) are stem-like cells that initiate and sustain tumor growth, and drive disease recurrence. Identifying therapies targeting BTIC has been hindered due primarily to their scarcity in tumors. We previously reported that BTIC frequency ranges between 15% a...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Gwynne, William D., Shakeel, Mirza S., Girgis-Gabardo, Adele, Kim, Kwang H., Ford, Emily, Dvorkin-Gheva, Anna, Aarts, Craig, Isaac, Methvin, Al-awar, Rima, Hassell, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404930/
https://ncbi.nlm.nih.gov/pubmed/32758183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07193-6
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