Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells

BACKGROUND: Breast tumor growth and recurrence are driven by an infrequent population of breast tumor-initiating cells (BTIC). We and others have reported that the frequency of BTIC is orders of magnitude higher when breast tumor cells are propagated in vitro as clonal spheres, termed tumorspheres,...

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Bibliographic Details
Published in:Cell Mol Biol Lett
Main Authors: Gwynne, William D., Shakeel, Mirza S., Wu, Jianhan, Hallett, Robin M., Girgis-Gabardo, Adele, Dvorkin-Gheva, Anna, Hassell, John A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Research Letter
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852929/
https://ncbi.nlm.nih.gov/pubmed/31754354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-019-0183-8
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