Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts

Breast tumors comprise an infrequent tumor cell population, termed breast tumor initiating cells (BTIC), which sustain tumor growth, seed metastases and resist cytotoxic therapies. Hence therapies are needed to target BTIC to provide more durable breast cancer remissions than are currently achieved....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gwynne, William D, Hallett, Robin M, Girgis-Gabardo, Adele, Bojovic, Bojana, Dvorkin-Gheva, Anna, Aarts, Craig, Dias, Kay, Bane, Anita, Hassell, John A
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458271/
https://ncbi.nlm.nih.gov/pubmed/28404880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16646
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