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Interferon-γ potentiates α-synuclein-induced neurotoxicity linked to toll-like receptor 2 & 3 and tumor necrosis factor-α in murine astrocytes
α-Synuclein (α-syn), an metabolite of neurons, induces glial activation and neuroinflammation and participates in pathogenesis of neurodegenerative diseases. This inflammatory response involves activation of toll-like receptors (TLRs) and its neurotoxic outcomes such as cytokine expression and relea...
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| Publié dans: | Mol Neurobiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7404632/ https://ncbi.nlm.nih.gov/pubmed/31098954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-1567-5 |
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