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α-Synuclein Activates Innate Immunity but Suppresses Interferon-γ Expression in Murine Astrocytes
Glial activation and neuroinflammation contribute to pathogenesis of neurodegenerative diseases, linked to neuron loss and dysfunction. α-Synuclein (α-syn), as a metabolite of neuron, can induce microglia activation to trigger innate immune response. However, whether α-syn, as well as its mutants (A...
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| Publicado no: | Eur J Neurosci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6949420/ https://ncbi.nlm.nih.gov/pubmed/29779267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13956 |
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