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Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy

Effective treatment of retinal diseases with adeno-associated virus (AAV)-mediated gene therapy is highly dependent on the proportion of successfully transduced cells. However, due to inflammatory reactions at high vector doses, adjunctive treatment may be necessary to enhance the therapeutic outcom...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Chandler, Laurel C., Yusuf, Imran H., McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E., Xue, Kanmin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404262/
https://ncbi.nlm.nih.gov/pubmed/32674481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21144972
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