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Systematic Humanization of the Yeast Cytoskeleton Discerns Functionally Replaceable from Divergent Human Genes

Many gene families have been expanded by gene duplications along the human lineage, relative to ancestral opisthokonts, but the extent to which the duplicated genes function similarly is understudied. Here, we focused on structural cytoskeletal genes involved in critical cellular processes, includin...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Garge, Riddhiman K., Laurent, Jon M., Kachroo, Aashiq H., Marcotte, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404242/
https://ncbi.nlm.nih.gov/pubmed/32522745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303378
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