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Systematic Humanization of the Yeast Cytoskeleton Discerns Functionally Replaceable from Divergent Human Genes

Many gene families have been expanded by gene duplications along the human lineage, relative to ancestral opisthokonts, but the extent to which the duplicated genes function similarly is understudied. Here, we focused on structural cytoskeletal genes involved in critical cellular processes, includin...

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Bibliografische gegevens
Gepubliceerd in:Genetics
Hoofdauteurs: Garge, Riddhiman K., Laurent, Jon M., Kachroo, Aashiq H., Marcotte, Edward M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404242/
https://ncbi.nlm.nih.gov/pubmed/32522745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303378
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