ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer

In this study we investigated the use of cancer cell protein expression of ABCG2 to predict efficacy of systemic first-line irinotecan containing therapy in patients with metastatic colorectal cancer (mCRC). From a Danish national cohort, we identified 119 mCRC patients treated with irinotecan conta...

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Pubblicato in:Int J Mol Sci
Autori principali: Palshof, Jesper Andreas, Cederbye, Camilla Natasha, Høgdall, Estrid Vilma Solyom, Poulsen, Tim Svenstrup, Linnemann, Dorte, Nygaard, Sune Boris, Stenvang, Jan, Christensen, Ib Jarle, Jensen, Benny Vittrup, Pfeiffer, Per, Brünner, Nils, Yilmaz, Mette, Viuff, Birgitte Martine, Nielsen, Dorte Lisbet
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404184/
https://ncbi.nlm.nih.gov/pubmed/32708825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145027
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