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Time-Restricted G-Protein Signaling Pathways via GPR176, G(z), and RGS16 Set the Pace of the Master Circadian Clock in the Suprachiasmatic Nucleus

G-protein-coupled receptors (GPCRs) are an important source of drug targets with diverse therapeutic applications. However, there are still more than one hundred orphan GPCRs, whose ligands and functions remain unidentified. The suprachiasmatic nucleus (SCN) is the central circadian clock of the bra...

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Pubblicato in:Int J Mol Sci
Autori principali: Nakagawa, Shumpei, Nguyen Pham, Khanh Tien, Shao, Xinyan, Doi, Masao
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404074/
https://ncbi.nlm.nih.gov/pubmed/32709014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145055
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