Time-Restricted G-Protein Signaling Pathways via GPR176, G(z), and RGS16 Set the Pace of the Master Circadian Clock in the Suprachiasmatic Nucleus

G-protein-coupled receptors (GPCRs) are an important source of drug targets with diverse therapeutic applications. However, there are still more than one hundred orphan GPCRs, whose ligands and functions remain unidentified. The suprachiasmatic nucleus (SCN) is the central circadian clock of the bra...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Nakagawa, Shumpei, Nguyen Pham, Khanh Tien, Shao, Xinyan, Doi, Masao
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404074/
https://ncbi.nlm.nih.gov/pubmed/32709014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145055
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