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Oxidative stress induces monocyte‐to‐myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma

BACKGROUND: Cancer‐associated fibroblasts (CAFs) are among the most prominent cells during the desmoplastic reaction in pancreatic ductal adenocarcinoma (PDAC). However, CAFs are heterogeneous and the precise origins are not fully elucidated. This study aimed to explore whether monocytes can transdi...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Huang, Xin, He, Chaobin, Hua, Xin, Kan, Anna, Mao, Yize, Sun, Shuxin, Duan, Fangting, Wang, Jun, Huang, Peng, Li, Shengping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403727/
https://ncbi.nlm.nih.gov/pubmed/32508052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.41
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