SYPL1 Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma via Suppression of ROS-Induced ERK Activation

Synaptophysin-like 1 (SYPL1) is a neuroendocrine-related protein. The role of SYPL1 in pancreatic ductal adenocarcinoma (PDAC) and the underlying molecular mechanism remain unclarified. Here, after analyzing five datasets (GSE15471, GSE16515, GSE28735, TCGA, and PACA-AU) and 78 PDAC patients from Su...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Song, Yunda, Sun, Xuesong, Duan, Fangting, He, Chaobin, Wu, Jiali, Huang, Xin, Xing, Kaili, Sun, Shuxin, Wang, Ruiqi, Xie, Fengxiao, Mao, Yize, Wang, Jun, Li, Shengping
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522464/
https://ncbi.nlm.nih.gov/pubmed/33042794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01482
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