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Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1

Trimetazidine (TMZ), as a metabolic regulator, is effective in treatment of coronary atherosclerotic heart disease with rare side effects in the clinic for long years. Interestingly, studies have shown that TMZ protects against several acute kidney injuries (AKI). However, the effect of TMZ on chron...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Yang, Yong, Wang, Yong, He, Zuowen, Liu, Yunchang, Chen, Chen, Wang, Yan, Wang, Dao Wen, Wang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403491/
https://ncbi.nlm.nih.gov/pubmed/32848753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01136
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