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Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy

Epithelial–mesenchymal transition (EMT) of renal tubular epithelial cells is one of the potential mechanisms of renal fibrosis, which promotes the development of diabetic nephropathy (DN). However, the molecular mechanisms of EMT remain largely unknown. Tuberous sclerosis proteins TSC1 and TSC2 are...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Lu, Qian, Chen, Yi-bing, Yang, Hao, Wang, Wen-wen, Li, Cheng-cheng, Wang, Lei, Wang, Jin, Du, Lei, Yin, Xiao-xing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468253/
https://ncbi.nlm.nih.gov/pubmed/31235817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0244-6
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